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[摘要] 目的 探討社会技能训练与家庭干预相结合对农村精神分裂症患者预后的影响。 方法 选择2017年3月～2018年2月期间宁波市慈溪、余姚等地四个社区的120例已纳入重性精神病防治管理网络，且病情稳定的农村康复期男性精神分裂症患者，随机分为两组，各60例。研究组在药物治疗的同时，采用社会技能训练程式结合家庭干预进行干预，对照组仅接受社区常规管理，不进行特殊干预。分别于入组时、3个月末和6个月末时采用阳性和阴性症状评定量表（PANSS）评定精神症状，个人和社会功能评定量表中国版（PSP-CHN）评定社会功能，采用正确服药天数评估服药依从性。 结果 研究组与对照组的一般资料PANSS评分无明显统计学差异，差异无统计学意义（F=0.236，P=0.844），而在3个月末和6个月末，研究组与对照组的PANSS总评分有统计学差异（F=4.852，P=0.033;F=12.687，P=0.001）;同时研究组社会功能均明显高于对照组（F=4.725，P=0.013;F=12.687，P=0.001），服药依从性均明显高于对照组，差异有统计学意义（F=6.038，P=0.014;F=15.917，P=0.000）。研究组在干预后精神病性症状、社会功能及服药依从性均好于干预前，对照组状况变差。 结论 精神分裂症技能训练结合家庭干预可进一步改善精神分裂症患者精神症状，提高服药依从性，促进社会功能的康复，有利于患者回归社会。
[关键词] 精神分裂症;技能训练;社会功能;服药依从性
[中图分类号] R161.7 [文献标识码] A [文章编号] 1673-9701（2019）28-0022-05
[Abstract] Objective To explore the impact of social skills training combined with family intervention on the prognosis of rural schizophrenia patients. Methods 120 patients with rural rehabilitation male schizophrenia who have been included in the severe psychiatric prevention and treatment management network and had stable disease in four communities including Cixi and Yuyao in Ningbo from March 2017 to February 2018 were randomly divided into two groups， with 60 cases in each group. The research team used social skills training program combined with family intervention as well as drug treatment. The control group only received routine management from the community without special intervention. Psychiatric symptoms were assessed at the time of eollment， at the end of 3 months， and at the end of 6 months using the Positive and Negative Symptom Rating Scale （PANSS）. The Personal and Social Function Rating Scale of Chinese Version （PSP-CHN） was used to assess social function. The number of correct medication evaluates medication compliance. Results There was no significant difference in the PANSS score between the study group and the control group （F=0.236， P=0.844）. At the same time， the social function of the study group was significantly higher than that of the control group（F=4.725， P=0.013， F=12.687， P=0.001）. While at the end of 3 months and 6 months， there were statistically differences in the total PANSS scores of the study group and the control group（F=4.852， P=0.033， F=12.687， P=0.001）. At the same time， the social function of the study group was significantly higher than that of the control group （F=4.725， P=0.013， F=12.687， P=0.001）， and medication compliance of the study group was significantly higher than that in the control group， and the difference was statistically significant（F=6.038， P=0.014， F=15.917， P=0.000）. After the intervention， the psychotic symptoms， social function and medication compliance of the study group were better than those before the intervention. And the condition of the control group became worse. Conclusion Schizophrenia skills training combined with family intervention can further improve the mental symptoms of patients with schizophrenia， improve medication compliance， promote the rehabilitation of social functions， and help patients return to society.